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Thomas Schmitt
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Thomas Schmitt

Thomas Schmitt

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6 Beiträge
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Thomas Schmitt
Thomas Schmitt
1 y

Human papillomavirus (HPV) is a large group of more than 150 related DNA viruses. HPV is named for the warts (papillomas) some types can cause and is spread through direct skin-to-skin contact. Although most HPV infections cause no symptoms and resolve spontaneously, some persist and result in warts or precancerous lesions. Of the more than 150 types, over 40 types are known to be transmitted through sexual contact and make it the most commonly sexually transmitted infection (STI).
HPV-induced cancers arise when viral sequences are integrated into the DNA of host cells. Some genes carried by the HPV virus, such as genes E6 and E7, act as oncogenes that promote tumor growth and malignant transformation. Roughly 12 HPV types (including 16, 18, 31, and 45) are classified as high-risk for being linked to malignancies. Nearly all cases of cervical cancer are associated with HPV infection, with two types present in 70% of cases: HPV16 and HPV18. Previous studies suggest that high-risk E7 oncoproteins are necessary for this cancer, by inactivating cell-cycle regulatory proteins. The ability to monitor these E7 levels may be a useful tool in cervical cancer screening and detection. https://www.creative-diagnosti....cs.com/human-hpv-16-

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Human HPV 16 E7 Oncoprotein ELISA Kit (DEIASL171) - Creative Diagnostics

Human HPV 16 E7 Oncoprotein ELISA Kit (DEIASL171), manufactured by Creative Diagnostics with high sensitivity and reproducibility, providing efficient and accurate result for lab research.
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Thomas Schmitt
Thomas Schmitt
1 y

Hepatitis A is a self-limited disease and chronic stage or other complications are rare. Infections occur early in life in areas with poor sanitation and crowded living conditions. With improved sanitation and hygiene, infections are delayed and consequently the number of persons susceptible to the disease increases. Because the disease is transmitted through the fecal-oral route, in dense populated regions an outbreak can arise from single contaminated source. The Hepatitis virus (HAV) is a Picornavirus; it is non-enveloped and contains a single-stranded RNA packaged in a protein shell. HAV has four major, structural polypeptides (VP1-4; 60 copies of VP1, 30-33 kD; VP2, 24-30 kD; VP3 (21-28 kD) and it localizes exclusively in the cytoplasm of human hepatocytes. The infection with HAV induces strong immunological response and elevated levels first of IgM and then IgG are detectable within a few days after the onset of the symptoms. IgG is an indicator of past infection and immunity to HAV. HAV is detected by the presence of HAV antigens or antibodies using ELISA. HAV occurs endemically in all parts of the world. https://www.creative-diagnosti....cs.com/human-anti-he

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Human Anti-Hepatitis A Virus IgG ELISA Kit (Quantitative) (DEIASL276) - Creative Diagnostics

Human Anti-Hepatitis A Virus IgG ELISA Kit (Quantitative) (DEIASL276), manufactured by Creative Diagnostics with high sensitivity and reproducibility, providing efficient and accurate result for lab research.
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Thomas Schmitt
Thomas Schmitt
1 y

Creative Diagnostics provides TCID50 Assay Service with a high level of assay sensitivity and accuracy. We have rich experience serving pharmaceutical, biotechnology, contract research, and academic scientists. Our TCID50 assays are used to assay drug sensitivity, quantify infectious units, determine the dose of virus required and study virus release. https://antiviral.creative-dia....gnostics.com/TCID50-

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50% Tissue Culture Infectious Dose Assay - Creative Diagnostics

Explore Creative Diagnostics' TCID50 Assay services for precise viral titer determination and antiviral research. Our specialized assays provide accurate insights into viral concentration and replication, aiding in drug development and virology studi
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Thomas Schmitt
Thomas Schmitt
1 y

Gastrointestinal (GI) cancer is a term used for the group of cancers that affect the gastrointestinal tract and other organs that are contained within the digestive system, including the esophagus, pancreas, stomach, colon, rectum, anus, liver, biliary system, and small intestine. https://reagents.creative-diag....nostics.com/research

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Gastrointestinal Cancer Drug Monitoring Reagents - Creative Diagnostics

Gastrointestinal (GI) cancer is a term used for the group of cancers that affect the gastrointestinal tract and other organs that are contained within the digestive system, including the esophagus, pancreas, stomach, colon, rectum, anus, liver, bilia
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Thomas Schmitt
Thomas Schmitt
1 y

HCP are impurities derived from host cell lysates and secreted or processed residues during the production of biologics that may reduce drug efficacy and may cause side effects. Anti-HCP antibodies are an effective method for removing HCP and can be used as a key tool in the development of assays to provide qualitative and quantitative analysis of HCP during the drug manufacturing process. https://qbd.creative-diagnosti....cs.com/products/anti

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Anti-HCP Antibodies - Creative Diagnostics

Creative Diagnostics can provide rigorously developed and manufactured anti-HCP antibodies that are successfully used for the identification and monitoring of HCP in numerous biopharmaceutical processes.
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