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Vidalista 80 is used to treat erectile dysfunction (ED) in men. Vidalista 80 contains Tadalafil, which is a phosphodiesterase type 5 (PDE5) inhibitor. PDE5 is an enzyme that breaks down a chemical called cyclic guanosine monophosphate (cGMP) in the penis. cGMP is responsible for relaxing the blood vessels in the penis, allowing more blood to flow into it, and causing an erection.