Malegra 200 mg blocks the phosphodiesterase type 5 (PDE5) enzyme, which relaxes the blood vessels in the penis and increases blood flow when a man is sexually aroused. This leads to improved erectile function. The effects usually begin 30 to 60 minutes after taking the tablet and can last up to 4–6 hours. This medication should be taken once a day, about one hour before sexual activity, with a full glass of water.

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